Like all scientific innovations, our story begins with key publications. In 2010, Ohio State University’s Drs. Gang Ruan and Jessica Winter, et al, foreshadowed the potential of MagDots in their paper, Simultaneous Magnetic Manipulation and Fluorescent Tracking of Multiple Individual Hybrid Nanostructures. The following year, Ruan and Winter redressed the endemic limitations of quantum dots in their paper Alternating-Color Quantum Dot Nanocomposites for Particle Tracking.
Their research outlined the opportunity to aggregate dots together in a protective polymer. The approach simultaneously mitigated against the blinking of single dots while providing a shield to prolong signal life.
In 2012, Winter and Ruan joined with Kunal Parikh and Kalpesh Mahajan to commercialize the technology. Core Quantum Technologies was established to bring their MultiDots and MagDots to market.