MagDot 575 nm CD3 – 20 Tests

$350.00

Product Description

The MagDot is a duel-purpose reagent, it combines quantum dots and superparamagnetic iron oxide particles within the same nanoparticle. Cells labeled with MagDots targeting specific antigens will be both fluorescent and magnetic. Therefore, after labeling cells of interest, one can look at the feed to determine the percent positive fluorescently via flow cytometry, and then place the labeled cells in a magnetic separator and analyze both the magnetic (for the enrichment) and the nonmagnetic (for the depletion) of targeted cells without the need for further fluorescent labeling.

These MagDots are conjugated to the OKT3 monoclonal antibody which specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale.

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Description

Product Information

Size

20 tests

Dilution*

20 µL/million cells

Host/Isotype

Mouse/IgG1

Class

Monoclonal

Type

Antibody

Clone

OKT3

Immunogen

Human CD3

Conjugate

575 nm MagDot

Form

Liquid

Purification

Purified

Storage Buffer

Borate, pH 7.4 with 0.5% BSA and 0.1% sodium azide

Storage Conditions

4˚C do not freeze

Reactivity

Human

Tested Application

Flow Cytometry and Magnetic Separation

Batch

Refer to lot on vial

*Suggested working dilution is given as a guide only.

It is recommended the user titrate the product for use in their own

experiment using appropriate negative and positive controls.

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