Protected by their polymer coating, MultiDots provide more photostability than existing quantum dots. Now you can store tagged cells and re-examine them later, without losing signal to photobleaching. When compared to Alexa dyes and other organic dyes, such as FITC, MultiDots do not photobleach when using powerful lasers, such in confocal microscopy.
Brightness and Excitation
At 5X the brightness of conventional quantum dots, MultiDots produce a powerful signal, even in photon-limited environments. The broad absorption spectrum shared by MultiDots of all colors means you can perform multiplex studies with a single light source. Meanwhile, the sharp spectral peaks produced will ensure your results are clear of emission overlap.
Although composed of several quantum dots, water-soluble MultiDots remain small enough to access the areas you need.
“…our electron microscopy has shown these novel nanoparticles can indeed get access to the myofilament lattice within muscle cells.” Prof. Beth Brainerd, Professor of Medical Science, Brown University
Fluorescent and Magnetic
Tag and separate rare targets while simultaneously evaluating cell surface expression. MagDots combine the enduring signal of MultiDots with superparamagnetic iron oxide nanoparticles (SPION) for sophisticated multimodal analyses. MagDots bring fluorescence and magnetism together at last.
The MultiDot format ensures there is a constant signal, even when individual dots within the polymer blink. This allows you to follow a target’s trajectory without drawing dotted lines. The MultiDot’s alternating color also helps microscopists determine when targets are leaving the focal plane or when they aggregate with other targets.